Comparative Efficacy of Polyamine-Based Scavenger Resins
نویسندگان
چکیده
منابع مشابه
Preclinical Antitumor Efficacy of the Polyamine Analogue
Certain N-abkylated analogues of the natural polyamine spermine have been found to disrupt pobyamine pool homeostasis and inhibit tumor cell growth. The most effective of these analogues, N’,N”-diethybnorspermine (DENSPM), apparently depletes intracellular pobyamine pools primarily by inducing the polyamine acetylating enzyme spermidine/ spermine N’-acetyltransferase, which contributes to polya...
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ژورنال
عنوان ژورنال: International Journal of Organic Chemistry
سال: 2012
ISSN: 2161-4687,2161-4695
DOI: 10.4236/ijoc.2012.21012